Mucosamin® References


Oral

          1. Cheng, K. K. F. et al. New measure of health-related quality of life for patients with oropharyngeal mucositis. Cancer. 2007: 109; 2590-2599
          2. Professional Dietetics. Mucosamin® Mouthwash Instructions for Use. 2016
          3. Professional Dietetics. Mucosamin® Oromucosal Spray Instructions for Use. 2016
          4. Lalla, R. V. Chemotherapy or radiation-induced oral mucositis. Dent Clin N Am. 2014: 58; 341-349
          5. Quinn, B. et al. Disseminating best practice in oral care: A national project: UKOMIC (The United Kingdom Oral Mucositis in Cancer Care Expert Group). 2013
          6. European Oncology Nursing Society. Oral mucositis guidelines. Available from: http://www.cancernurse.eu/documents/ EONSClinicalGuidelinesSection4-en.pdf [Accessed May 2016]
          7. Campos, M. et al. Oral mucositis in cancer treatment: Natural history, prevention and treatment (review). Mol Clin Oncol. 2014: 2; 337-340
          8. The Oral Cancer Foundation. Mucositis. Available from: http://oralcancerfoundation.org/complications/mucositis.php [Accessed May 2016]
          9. National Health Service, UK. Mucositis. Available from: http://www.nhs.uk/conditions/mucositis/Pages/Introduction.aspx [Accessed May 2016]
          10. Kumar, N. et al. The oral management of oncology patients requiring radiotherapy, chemotherapy and/or bone marrow transplantation. Available from: https://www.rcseng.ac.uk/fds/publications-clinical-guidelines/clinical_guidelines/documents/clinical-guidelines-for-the-oral-management-of-oncology-patients-requiringradiotherapy-chemotherapy-and-or-bone-marrowtransplantation [Accessed May 2016]
          11. Ruggiero, T et al. Use of sodium hyaluronate and synthetic amino acid precursors of collagen for the symptomatic treatment of mucositis in patients undergoing haematopoietic stem cell transplants. 2016: 30(3)
          12. Colella, G. et al. Efficacy of a spray compound containing a pool of collagen precursor synthetic amino acids (L-Proline, L-Leucine, L-Lysine and Glycine) combined with sodium hyaluronate to manage chemo/radiotherapy-induced oral mucositis. Int J Immunopathol Pharmacol. 2010: 23(1): 143-151
          13. Vescovi, P. et al. Effects of amino acids and sodium hyaluronate (Aminogam) in the post operative period after surgical laser treatment of oral lesions: A pilot study.
          14. Corsalini, M. et al. Sterile gel based on sodium hyaluronate and amino acids: Bone healing biological mechanisms in patients treated for third stage bisphosphonates-related osteonecrosis of the jaws (BRONJ). International Symposium Osteology Monaco.
          15. Cirillo, N. A hyaluronic acid-based compound inhibits fibroblast senescence induced by oxidative stress in vitro and prevents oral mucositis in vivo. J of Cell Phys. 2014.
          16. Romeo, U. et al. Oral soft tissue wound healing after laser surgery with or without a pool of amino acids and sodium hyaluronate: A randomized clinical study. Photomed Laser Surg. 2014: 32; 10-16
          17. Favia, G. et al. Accelerated wound healing of oral soft tissues and angiogenic effect induced by a pool of amino acids combined to sodium hyaluronate (Aminogam). J Biol Regul Homeost Agents. 2008: 22(2): 109-116
          18. Colella, G. et al. Amino acid-enriched sodium hyaluronate enhances keratinocyte scattering, chemotaxis and wound healing through ß1-dependent mechanisms. J of Stomatol Invest. 2009: 3: 21-29


  1. Dermal

          1. The Princess Royal Radiotherapy Review Team. Managing radiotherapy induced skin reactions. St James’s Institute of Oncology. 2011.
          2. Salvo, N. et al. Prophylaxis and management of acute radiation-induced skin reactions: A systematic review of the literature. Curr Oncol. 2010: 17(4); 94-112.
          3. Professional Dietetics. Radioderm Instructions for use. 2016
          4. Chan, R. J. et al. Prevention and treatment of acute radiation-induced skin reactions: A systematic review and meta-analysis of randomized controlled trials. BMC Cancer. 2014: 14(53).
          5. Kearney, N. et al. Nursing patients with cancer. 1st ed. London: Elsevier Limited; 2006
          6. Glover, D. and Harmer, V. Radiotherapy-induced skin reactions: Assessment and management. Br J Nurs. 2014: 23(4)


  1. Rectal

          1. Do, N. L. et al. Radiation proctitis: Current strategies in management. Gastroeneterol Res Pract.
          2. Professional Dietetics. Mucosamin Rectal Gel Instructions for Use. 2016
          3. Pal, N. Radiation enteritis and proctitis. Available from: http://emedicine.medscape.com/article/197483-overview [Accessed November 2016]
          4. Wu, X. et al. Pathogenesis, diagnosis, and management of ulcerative proctitis, chronic radiation proctopathy, and diversion proctitis. Inflamm Bowel Dis. 2015: 21; 703-715
          5. Andreyev, J. Gastrointestinal symptoms after pelvic radiotherapy: A new understanding to improve management of symptomatic patients. Lancet Oncol. 2007: 8; 1007-1017
          6. Jones, K. et al. Treatment of radiation proctitis with hyperbaric oxygen. Radiother Oncol. 2006: 78; 91-94
          7. Lee, C. S. et al. Gastro-intestinal toxicity of chemotherapeutics in colorectal cancer: The role of inflammation. World J Gastroenterol. 2014: 20(14); 3751-3761
          8. Macmillan Cancer Support. Throwing light on the consequences of cancer and its treatment. Available from: http://www.macmillan.org.uk/documents/aboutus/research/researchandevaluationreports/throwinglightontheconsequencesofcanceranditstreatment.pdf [Accessed November 2016]



  1. Vaginal

          1. Jensen, P. T. and Froeding, L. P. Pelvic radiotherapy and sexual function in women. Trans Androl Urol. 2015: 4(2); 186-205
          2. Professional Dietetics. Mucosamin® Vaginal Cream Instructions for Use. 2016
          3. Mayo Clinic. Cancer treatment can cause physical changes that make having sex more difficult. Available from: http://www.mayoclinic.org/diseases-conditions/cancer/in-depth/cancer-treatment/art-20047214?pg=2&p=1 [Accessed November 2016]
          4. Krychman, M. L. et al. Chemotherapy-induced dyspareunia: A case study of vaginal mucositis and pegylated liposomal doxorubicin injection in advanced stage ovarian carcinoma. Gynecol Oncol. 2004: 93; 561-563
          5. Miles, T. et al. International guidelines on vaginal dilation after pelvic radiation. Available from: http://www.ncsi.org.uk/wp-content/uploads/Inter-Best-Practice-Guide-Vaginal-Dilators-July-2012.pdf [Accessed November 2016]
          6. Juraskova, I and Lubotzky, F. Recovering after pelvic radiation therapy: A guide for women. Available from: http://www.targetingcancer.com.au/wp-content/uploads/2015/10/Recovering-after-Pelvic-Radiation-Therapy-a-guide-for-women.pdf [Accessed November 2016]