Mucosamin® and Radioderm® contains sodium hyaluronate and amino acids.1,2,3,4
For radio-chemotherapy induced mucositis and dermatitis.

Sodium hyaluronate

Sodium hyaluronate is the sodium salt of hyaluronic acid. Hyaluronic acid is a key component of connective tissue and promotes tissue repair. Its use has also been reported in dentistry to exert an anti-inflammatory effect and to control gingival bleeding.5 Hyaluronic acid in Mucosamin® and Radioderm® has been shown to promote cell proliferation, differentiation and motility.6

Amino Acids

The amino acids present in Mucosamin® and Radioderm® are intended to promote the formation of collagen.1,2 The availability of amino acids, such as those present in Mucosamin® and Radioderm®, is necessary in wound repair due to increased metabolic activity.6,7 The amino acids present in Mucosamin® and Radioderm® favour wound healing by collagenogenesis and extracellular matrix (ECM) formation.7

What is
oral mucositis?

Oral mucositis is an acute inflammatory and ulcerative complication of the mucosal membrane that commonly occurs during cancer therapy.6

The primary morbidity of oral mucositis is intense pain, which is usually associated with ulcerative lesions.9 It can also cause dysphagia and impairment of the ability to talk, eat and swallow.10

Mucosamin® oral range has proven effectiveness for all approved indications:


What are
Mucosamin® Oral products?

Mucosamin® oral range helps in the process of regeneration of the oral mucosa before, during and after radio-chemotherapy.1,2

Mucosamin® oral products are available in two different presentations, a mouthwash and a spray.

Mucosamin® Mouthwash

Mucosamin® Mouthwash is a topical oral solution used to help in the prevention and treatment of oral mucositis induced by cancer treatment.1

Mucosamin® Spray

Mucosamin® Spray is a fluid gel used to help in the treatment of oral mucositis induced by cancer treatment. The spray formulation allows difficult areas of the mouth to be reached.2

What is
radiation proctitis?

Radiation proctitis is a radiation induced rectal mucositis and is defined as an inflammatory process of the rectal mucosa that occurs almost immediately after the initiation of therapy or up to 3 months after the onset of radiotherapy. Symptoms of acute radiation proctitis include burning pain sensations, diarrhoea, nausea, cramps, tenesmus, urgency, mucous discharge and minor bleeding.11

Mucosamin® Rectal Gel supports the healing of the rectal mucosa following cancer treatment4

What is
Mucosamin® Rectal Gel?

Mucosamin® Rectal Gel is an adjuvant in the healing process of the rectal mucosa during radio-chemotherapy.1,2

Mucosamin® Rectal Gel

Mucosamin® Rectal Gel is an adjuvant in the healing process of the rectal mucosa, and as treatment in the painful symptomatology of rectal mucositis caused by radiotherapy and/or chemotherapy of pelvic tumours.

Mucosamin® Rectal Gel treatment of rectal mucositis improves mucosa tropism, and is designed to prevent the onset of rectal mucositis and also avoid recurrence.2

What are the effects of chemotherapy and
pelvic radiotherapy?

Chemotherapy can damage the vaginal tissue, which can lead to ulcerations or disruptions in the integrity of the mucosa, and increase the risk of infection.12 Chemotherapy drugs that may cause mucositis can also cause vaginal irritation.13

The vaginal and vulval epithelium are highly sensitive to the effects of pelvic irradiation or pelvic radiotherapy due to rapid cell-turnover.15

Mucosamin® Vaginal Cream supports the healing of the vaginal mucosa following cancer treatment3

Radiotherapy to the pelvic region can damage vaginal epithelium, connective tissues and small blood vessels, causing inflammation and cell death prior to resolution. The subsequent reduced blood supply, tissue hypoxia, loss of elastin, collagen deposition and hyalinisation and fibrosis leads to thinning of the vaginal mucosa, loss of lubrication, scarring and fibrosis.15

Following pelvic radiation, acute radiation effects include vaginal erythema, moist desquamation and a confluent mucositis. The mucosa may demonstrate severe congestion and submucosal haemorrhage.14

What is
Mucosamin® Vaginal Cream?

Mucosamin® Vaginal Cream

Mucosamin® Vaginal Cream helps with the healing process of the vaginal mucosa and aids the treatment of painful symptoms of neurological injury caused by vulvovaginitis due to radiotherapy and/or chemotherapy of pelvic tumours3

What is
radiation dermatitis?

Radiation dermatitis is an acute skin reaction which can range from mild erythema to confluent moist desquamation and ulceration.16 It is one of the most common side effects of radiation therapy.16, 17

Radiation dermatitis is caused by a disruption of the normal process of cell division and regeneration resulting from radiation treatment, which leads to cell damage or death.18

Radioderm® helps with the prevention and treatment of dermatitis during radiotherapy4

The acute damage done to the skin by radiation is uniquely different from all other forms of skin damage.19

Radiation dermatitis is often characterised by swelling, redness, pigmentation, fibrosis and ulceration of the skin. Symptoms are expressed as pain, warmth, burning and itching of the skin.18

What is
Radioderm®?

Radioderm®

Radioderm® protects the skin in the early stages of lesions or dermatitis, which are caused by radiotherapy. It has a preventative effect on the progression of tissue damage and reduces redness, itching and burning in the area exposed to ionising radiation, promoting completion of treatment without unwanted withdrawals or delays.4