MUCOSAMIN® ORAL

Mucosamin® oral products help in the process of regeneration of the oral mucosa.2,3
Mucosamin® oral products are available in two different presentations, a mouthwash and a spray.


Mucosamin® Mouthwash

Mucosamin® Mouthwash is a topical oral solution used to help in the treatment and prevention of oral mucositis induced by cancer treatment.2

Mucosamin® Spray

Mucosamin® spray is a fluid gel used to help in the treatment of oral mucositis induced by cancer treatment. The spray formulation allows difficult areas of the mouth to be reached.3

The primary morbidity of oral mucositis is intense pain, which is usually associated with ulcerative lesions.4 It can also cause dysphagia and impairment of the ability to talk, eat and swallow.5

The inflammation in oral mucositis can range from erythema to severe ulceration, and is typically associated with pain and discomfort.6

Oral mucositis can cause profound psychological distress and impairment of quality of life for cancer patients1 due to pain and inability to eat solid foods.7 This can lead to the use of nasogastric tube placement or total parenteral nutrition use.

Oral mucositis is one of the more significant side-effects of cancer treatment. Oral mucositis can result from systemic chemotherapy, from radiation therapy, or a combination of the two.4

When caused by chemotherapy, oral mucositis is usually due to the low white blood cell count. When caused by radiotherapy, oral mucositis is usually due to the necrotic and inflammatory effect of ionising radiation on oral mucosa.8

All chemotherapy drugs have the potential to cause oral mucositis.5 Treatments most commonly associated with oral mucositis include:

• Anti-metabolites (e.g. fluorouracil, capecitabine, methotrexate)

• Anthracyclines (e.g. epirubicin, doxorubicin)

• All lymphoma or leukaemia patients who have recently had treatment

• Tyrosine kinase inhibitors (such as sunitinib, pazopanib, afantinib) and everolimus

• Radiotherapy to the head and neck region.5

What is Mucosamin®?

Mucosamin® oral products help in the process of regeneration of the oral mucosa.2,3
Mucosamin® oral products are available in two different presentations, a mouthwash and a spray.

Mucosamin® Mouthwash

Mucosamin® Mouthwash is a topical oral solution used to help in the treatment and prevention of oral mucositis induced by cancer treatment.2

Mucosamin® Spray

Mucosamin® Spray is a fluid gel used to help in the treatment of oral mucositis induced by cancer treatment. The spray formulation allows difficult areas of the mouth to be reached.3

Mucosamin® Mouthwash and Mucosamin® Spray are formulated to help the process of regeneration of the oral mucosa, promote healing of areas of ulceration, and reduce local sensitivity within the mouth.2,3


Mucosamin® has multiple effects:

  • It has a predominantly protective action and helps to hydrate2,3 provides pain relief 12,13,14 and promotes repair of the oral mucosa.2,3
  • In addition, Mucosamin® Mouthwash can be used to help the reduce incidence of oral mucositis.2,3

When should
Mucosamin® be used?

Mucosamin® Mouthwash

  • At the start of radiological therapy or chemotherapy to help to reduce the incidence of oral mucositis.2,15
  • To help in the treatment of radiotherapy or chemotherapy induced oral mucositis..2,12
  • To help in the treatment of ulcerative pathologies of the oral cavity (e.g. pemphigus, pemphigoid, erosive lichen planus).2
  • To help in the treatment of recurrent aphthous stomatitis.2
  • To help in the treatment following surgical operations on the tongue and oral mucosa.2,14,16,17
  • To help in the treatment of burning mouth syndrome.2

Mucosamin® Spray

To help in the treatment of radiotherapy or chemotherapy induced oral mucositis.3,21

How does
Mucosamin® work

Mucosamin® contains hyaluronic acid (sodium hyaluronate), which is the main component of connective tissue and amino acid precursors of structural proteins of the extracellular matrix.2,3,12

Mucosamin® is an approved medical device and consists of a natural polysaccharide that forms a mucoadhesive layer on the surface epithelial cells of the oral mucosa.2,3

Mucosamin® is an approved, Class IIa, medical device which acts on the surface of the oral mucosa.2,3

a) Forming a protective barrier that helps promote healthy regeneration of tissue (this is its main “mode of action”).2,3

b) Hyaluronic acid and amino acids help the reepithelialisation of the oral mucosa, helping to stimulate cell growth.2


When used at the start of chemotherapy or radiotherapy, Mucosamin® Mouthwash hydrates and protects the oral mucosa, in order to help to reduce the incidence of mucositis.2
Mucosamin® can be used to hydrate the oral mucosa.2,3
Mucosamin® creates a protective film that covers and helps to protect the mucosa, helping to reduce the pain and burning sensations induced by oral mucositis.2,3
Mucosamin® creates a protective film that covers and helps to protect the mucosa.2,3 Mucosamin helps to promote the wound healing process and repair of the oral mucosa.2,3,18